- Sabas, Patriarchal Abbot in Palestine
- Sabina (and Seraphia), Martyrs
- Sabinus, Bishop of Spoleto, and his Companions, Martyrs
- Sanctus and Forty-Eight other Martyrs of Lyons
- Saturninus, Bishop and Martyr
- Scholastica, Abbess
- Sebaste, The Forty Martyrs of Sebaste
- Sebastian, Martyr
- Sennen (and Abdon), Martyrs
- Seraphia and Sabina, Martyrs
- Servulus of Rome, Invalid and Beggar
- Seven Holy Servite Founders
- Seven Sorrows of the Blessed Virgin Mary
- Severianus, Bishop and Martyr
- Severinus, Abbot
- Sharbel (Charbel) Makhlouf, Maronite Priest and Hermit
- Silverius, Pope and Martyr
- Simeon Stylites
- Simon and Jude, Apostles and Martyrs
- Simon Stock
- Soter and Caius, Popes, Martyrs
- Stanislaus, Bishop of Cracow, Martyr
- Stanislaus Kostka, Jesuit, Patron of Youth
- Stephanie Quinzani, Virgin
- Stephen, Protomartyr
- Stephen: the Finding of Saint Stephen's Relics
- Stephen I, Pope and martyr
- Stephen, King of Hungary
- Stigmata of Saint Francis
- Susanna, Virgin and Martyr
- Sylverius, Pope and Martyr
- Sylvester, Pope and Confessor
- Symphorian, Martyr